Thorne’s 5-MTHF provides L-5-methyltetrahydrofolate, the active and bioavailable form of folate. This form is ready for the body to use and is ideal for individuals who have difficulty converting synthetic folic acid into active folate due to genetic factors or digestive or liver challenges.*

Many people, including an estimated three out of five Americans, do not efficiently convert folic acid into 5-MTHF.* Supplementing with active folate helps ensure consistent support for methylation, mood, and overall health.*

Key benefits:

• Provides active folate (5-MTHF), the usable form of folic acid*

• Supports healthy mood and emotional well-being*

• Plays a role in the production of serotonin, dopamine, melatonin, and norepinephrine*

• Supports healthy methylation and DNA synthesis*

• Helps maintain already-normal homocysteine levels*

• Ideal for individuals with MTHFR genetic variations*

Important support for women of childbearing age
Adequate folate intake is essential for women of childbearing age, not only those planning pregnancy.* Because many pregnancies are unplanned, daily folate support is especially important before conception and during early pregnancy, when folate needs are highest.*

Supplementation with 5-MTHF is preferred over folic acid because it does not require conversion and is immediately available for use by the body.*

Methylation and metabolic support
Working alongside vitamin B12, 5-MTHF acts as a methyl-group donor, helping convert homocysteine to methionine.* Methylation is essential for neurotransmitter production, DNA synthesis, and numerous biochemical processes throughout the body.*

Suggested use:

• Take 1 capsule one to two times daily

• Or as recommended by your health professional

Supplement Facts:

• Serving Size: 1 Capsule

• Folate: 8.3 mg DFE

  • (as L-5-Methyltetrahydrofolate)

Other Ingredients:

• Hypromellose Capsule

• Leucine

• Microcrystalline Cellulose

• Silicon Dioxide

Important information:

• Allergy warning: Do not use if sensitive to any ingredient

• Pregnancy: Consult your health professional before use

• Interactions: 5-MTHF should not be used with methotrexate cancer therapy. Individuals taking methotrexate for non-cancer conditions may use folate under professional guidance

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.